The Higuchi model is a mathematical model used to describe the release of drugs from a solid matrix, primarily focusing on diffusion-controlled release mechanisms. It is particularly useful for predicting the release kinetics of drugs from non-swelling, porous matrices over time, assuming a constant diffusion coefficient and a uniform initial drug distribution.

Higuchi Model

A mathematical model is a representation of a system using mathematical concepts and language, enabling analysis, prediction, and understanding of complex phenomena. These models are crucial in fields such as physics, economics, and engineering, where they help simulate real-world processes and guide decision-making.

Mathematical Model

Release of drugs

A solid matrix is an organized arrangement of atoms or molecules resulting in a three-dimensional structure with defined boundaries. This matrix can significantly affect material properties like strength, conductivity, and reactivity, depending on the constituent elements and their bonding types.

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