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Dihydropyrimidinase is an enzyme that plays a crucial role in the catabolism of pyrimidines, specifically by catalyzing the hydrolytic ring opening of dihydropyrimidines to N-carbamyl-β-amino acids. Deficiencies in this enzyme can lead to disorders such as dihydropyrimidinuria, characterized by the accumulation of dihydropyrimidines in the urine.
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