Alzheimer's disease is a progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes, primarily affecting older adults. It is the most common cause of dementia, with complex pathophysiology involving amyloid-beta plaques, tau tangles, and neuroinflammation, leading to neuronal death and brain atrophy.

Alzheimer's Disease

Alzheimer's disease

progressive neurodegenerative disorder

Memory loss refers to an unusual forgetfulness that can affect both the short-term and long-term memory. It can stem from various causes, including aging, injury, illness, or psychological stress, and knowing the exact cause is crucial for proper management and treatment.

memory loss

Cognitive decline refers to the gradual deterioration of cognitive abilities, including memory, reasoning, and problem-solving skills, often associated with aging or neurological disorders. It can significantly impact daily functioning and quality of life, making early detection and intervention crucial for managing its effects.

cognitive decline

Behavioral changes refer to the modifications in an individual's actions, reactions, and interactions, often as a response to internal or external stimuli. These changes can be temporary or permanent and are influenced by psychological, environmental, and biological factors.

behavioral changes

older adults

most common cause of dementia

complex pathophysiology

amyloid-beta plaques

Tau tangles are abnormal accumulations of tau protein that form inside neurons, disrupting the cell’s transport system and leading to cell death. They are a hallmark of neurodegenerative diseases such as Alzheimer's, contributing to cognitive decline and memory loss.

tau tangles

Neuroinflammation is the inflammatory response within the brain or spinal cord, often involving the activation of glial cells, which can play a dual role in both protecting and potentially damaging neural tissue. This process is implicated in various neurological disorders, including Alzheimer's disease, multiple sclerosis, and traumatic brain injury, highlighting its significance in both the pathology and potential therapeutic strategies for these conditions.

neuroinflammation

Neuronal death is a critical process in the nervous system that can occur due to injury, disease, or programmed mechanisms like apoptosis, impacting brain function and contributing to neurodegenerative conditions. Understanding the pathways and triggers of neuronal death is essential for developing therapeutic strategies to prevent or mitigate neurological disorders.

Relevant Degrees

Your Lessons